The Bredesen Alzheimer’s Disease Reversal Protocol

Unless a person is suffering from advanced Alzheimer’s disease, this neurodegenerative disease has  recently been shown by Dr Bredesen to be reversable with holistic medicine. (1)

Dr. Dale Bredesen,  of the Buck Institute for Research on Aging, has unequivocably demonstrated with a small cohort of ten patients that A.D. reversal is indeed possible, (2) but only if a synergistic holistic approach is used. Each intervention is tweaked over time by using blood tests, body measurements, imaging and similar guides to measure its effect.

Dr. Bredesen has since expanded and refined the protocol. Since the 2014 protocol publication based on this small cohort of patients, he has used his holistic approach on hundreds of other Alzheimer’s patients. With unprecedented success thereby proving beyond any reasonable doubt that conventional medicine’s pharmaceutical drug approach is unavailing for the task of reversing this dreaded disease. Dr Bredesen is in the process of making his protocol available to the wider public with the help of doctors certified in the protocol through MPI Cognition.

The Happiness Medicine Institute team has followed Dr Bredesen’s work with interest and is doing its best to also contribute in meeting this challening, including with advanced Alzheimer Diseased patients.

In the Institute’s workshops and pending ebook, we have focused on other complementary holistic interventions that Dr Bredesen has not used.

Pending more funds to show H.M. Institute’s success in this field, hereinafter Dr Bredesen’s 25 steps, which is a great way to start the A.D. reversal process for the benefit of mild Azheimer patients.

 The Bredesen Protocol to reverse Alzheimer Disease

1. Optimize diet

2. Enhance autophagy, ketogenesis

3. Reduce stress

4. Optimize sleep

5. Exercise

6. Brain stimulation

7. Homocysteine less than 6 (earlier version of the protocol was < 7)

8. Serum B12 greater than 500

9. CRP less than 1.0; A/G greater than 1.8 (earlier version of the protocol was > 1.5)

10. Fasting insulin less than 5; HgbA1c less than 5.6 (earlier version of the protocol was Fasting insulin <7; HgbA1c <5.5)

11. Hormone balance

12. GI health

13. Reduction of Aß

14. Cognitive enhancement

15. 25OH-D3 = 50-80ng/ml (earlier version of the protocol was 50-100)

16. Increase NGF

17. Provide synaptic structural components

18. Optimize antioxidants

19. Optimize Zn:fCu ratio

20. Ensure nocturnal oxygenation

21. Optimize mitochondrial function

22. Increase focus

23. Increase SirT1 function

24. Exclude heavy metal toxicity

25. MCT effects

26. Inhalational Alzheimer’s

Lab testing information

Supplement ordering

Reference Notes

(1). Dr Bredesen’s book, The End of Alzheimer’s: The First Program to Prevent and Reverse Cognitive Decline, published August 22, 2017.  Amazon link to Dr Bredesen’s book
The first version of Dr Bredesen’s protocol (which is similar to the above) can be found in his paper: Reversal of cognitive decline: A novel therapeutic program, published September 2014, https://www.ncbi.nlm.nih.gov/pubmed/25324467
(2). In his initial paper, nine out of ten patients reversed their memory problems and returned to their former healthy level of functioning. The one who didn’t show improvement was past the early stages of Alzheimer’s

Videos and interviews

Videos are available on the MPI Cognition website www.mpicognition.com
There is a long, but very good STEM Talk interview with Dr Bredesen available on YouTube, Published on Jun 1, 2016 Episode 12 Dale Bredesen discusses the metabolic factors underlying Alzheimer’s Disease
Presentation given by Dr Bredesen at the Integrative Healthcare Symposium (IHS) Pre-Conference – Feb. 24, 2016 in Midtown, New York City IHS 2016 -Cognitive Health: Dawn of the Era of Treatable Alzheimer’s Disease
36 Holes in the Roof, comes with a very nice illustrative video, published Mar 25, 2015 36 ‘Holes in the Roof’ The Dawn of the Era of Treatable and Preventable Alzheimer’s Disease
Dr Gundry’s interview with Dr Bredesen, Published on Aug 21, 2017 Dr. Steven Gundry interviews Dr Dale Bredesen about “The End of Alzheimer’s”
Dr Mercola’s interview with Dr Bredesen, with a fair discussion of ApoE4, Published on Aug 25, 2017, Dr. Mercola Interviews Dr. Bredesen About ReCODE Protocol

Other related papers from Dr Bredesen

Metabolic profiling distinguishes three subtypes of Alzheimer’s disease, published in August 2015, https://www.ncbi.nlm.nih.gov/pubmed/26343025
Direct Transcriptional Effects of Apolipoprotein E published January 2016, Dr Bredesen is co-author.  https://www.ncbi.nlm.nih.gov/pubmed/26791201
Inhalational Alzheimer’s Disease: An unrecognized – and treatable epidemic, published February 2016. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789584/
Transcriptional Effects of ApoE4: Relevance to Alzheimer’s Disease, published September 2017. https://www.ncbi.nlm.nih.gov/pubmed/28879423

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Disclaimer: Nothing is this educational blog should be construed as medical advise
2017 (c) Happiness Medicine Institute and agents. All rights reserved

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