Casomorphin is an opioid peptide (protein fragment) derived from the digestion of the milk protein casein.
Digestive enzymes can break casein down into peptides that have some biological activity in cells and in laboratory animals though conclusive causal effects on humans have not been fully established. Although they have not yet been proven to be formed in the human digestive system, there are serious associations between serum levels of β-casomorphins and the risk of sudden infant death syndrome, histamine release, stimulation of food intake, specifically high-fat foods, and lymphocytosis..
There may be a link between autism and both gluten and casein..
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