- 1 Section A
- 2 The Evidence with regard to Carnitine-rich Animal Foods
- 3 Mechanism
- 4 The Evidence with high Choline rich Foods
- 5 Cases in pont: Prostate, Multiple Myeoloma and Colo-rectal Cancers
- 6 The Vegan exception
- 7 Parasites in Animal Foods
- 8 Harvard University Corroboration
- 9 Cancer Biology 101
- 10 Mechanism
- 11 Discussion & Conclusion
- 12 References
Animal Cholesterol, saturated fats, heme iron, uric acid, parasites, excess cortisol, acidity, heavy metals and, among other deleterious molecules and toxic residues are not the only problems with animal foods. Another reason is associated with too much carnitine in meat and choline in fish and eggs. We need a little carnitine and choline and in the right proportion for the correct expression of DNA transcription to occur. But like sex, salt, sleep, exercises and wine, too much of a good thing is harmful. In this analysis, I will first look at the recent evidence that condems meat as a human food (Section A) and thereafter, connect the dotes insofar as what the best available research suggests. (Section B)
The Evidence with regard to Carnitine-rich Animal Foods
In this perspective, a research team at the Cleveland Clinic found that within 24 hours of carnitine consumption (in the form of a sirloin steak), the “bad guys” gut bacteria metabolize the carnitine to a toxic substance called trimethylamine, which then gets oxidized in the liver to TMAO (trimethylamine-n-oxide), which then circulated throughout the bloodstream and promoted massive cardio-vascular problems. (Source)
The mechanism behind this TMAO process is related to the micro-environment of the endothelial wall with regard to the buildup of cholesterol and the inflammatory cells in the atherosclerotic plaques in human arteries, that which increases the risk of heart attack, stroke and death. (Source)
The evidence that supports this assertion came from an experimentation where the researchers wiped out gut bacteria in humans and fed them all of the steak they wanted. No TMAO was produced. And when they waited a few weeks for the gut bacteria to replenish and fed these humans meat, the TMAO was produced. (ibid.).
Moreover, the more omnivores ate meat, the more they fed these TMAO producing bacteria.
On the other hand, when a human gut has been predominantly vegan with lots of plant-based fibers, that human has a gut rich in short fatty chain producing fiber-loving intestinal bacteria that does not produce TMAO, even when on rare occasions the vegan may slip and consume fish-based meals, notwithstanding some exception with the improved Mediterranean diet (See Discussion)
The Evidence with high Choline rich Foods
Furthermore, carnitine-rich meat is not the only TMAO source, all sources of high choline are also a problem, even vegan sources. In this perspective, eggs, milk, liver, poultry, shell fish, and fish are high in choline, thus the gut bacteria also converts choline into TMAO production. (Source) Same effect with carnitine and choline rich processed vegan foods where these two molecules are exogenously added by those scientists who work for the billion dollars booming vegan process meal industry.
Given the similarity in structure between carnitine and choline, these gut bacteria react against the choline like they do against the carnitine. (Source)
Cases in pont: Prostate, Multiple Myeoloma and Colo-rectal Cancers
These two deleterious molecules (in excess) dont only affect the cardio-vascular system, they also impact cancer cells. In a recent published study, it was found that those who ate the most choline-rich foods like eggs had a 70% increased risk of lethal prostate cancer. (Source A) & (Source B)
Animal cholesterol also potentiates the choline, as both substances are inflammatory and deleterious to one’s human health. So the more animal foods, the worse it is for longevity and health.
The Vegan exception
Unlike carnitine, which can be synthesized by the body, vegans do need to take in some choline, and they do via beans, veggies, grains, and certain fruit. There’s also a small amount of carnitine found in fruits, veggies, and grains, as well.
So the test issue is to see if this smaller dosage of carnitine and choline in plant-based diets also trigger TMAO. Scientists looked at this question. Their results were stunning. Not only vegan sources of choline and carnitine did not promote TMAO, but even if they ingested tons of carnitine and choline, vegans would still not make TMOA. (Source)
At least in the short run. Why is this ? Because it takes some time to develop those TMAO-producing bacteria in the gut. Over-doing it with choline and carnitine for a short period will not be enough time to get the bad TMAO bacteria to develop and form their TMAO endotoxins and metabolites.
Non holistic vegans also have to be careful because of the carnitine-containing energy drinks, or carnitine supplements, or even lecithin supplements many take as they all contain way to much choline, enough to maintain those same kinds of TMAO-producing bacteria in the gut, that which significantly increases the risk of heart disease and cancer.
As we know, in medicine and in particular, drugs, supplements, wine and the like, dosage is key. A little too much and the opposite effect is unleashed.
Parasites in Animal Foods
In addition to animal cholesterol, animal saturated fats, endotoxins, hormones, antibiotics and, inter alia, MTOA (from carnitine and choline), there is also the issue of parasites and cancer like leukemia in animal foods. Yes, lots of leukemia in American cows. (Source)
Let’s just take lamb chops, eaten and promoted by many misguided “health gurus” like Drs. Mercola, Hymans, Berg and other medical paleo-keto doctors and nutritionists. The prevalence of the parasite Toxoplasma in lamb is high. Around 1 in 6 of U.S. lambs are actively infected. This means that about 10% of Americans are currently infected with this brain parasite. (Source)
In this perspective, the research has shown a direct causal connection between these Toxoplasma brain parasites and schizophrenia, bipolar disorder, and Parkinson’s. (Ibid.)
When the immune system starts to seriously slip, though, these parasites can also infect our eyeballs, then bye bye good vision. (Source).
As for Alzheimer’s disease, if the borella bacteria from Lyme disease can promote Alzheimers, it can be assumed that lamb parasites can also do this. In 16-17th centuries France, one of the poisons of choice to get rid of someone was to hang upside down a pig, let it’s blood and other fluids fill a big container, and allow the the raw liquid to macerate for many weeks when the bacteria and parasite-rich final product would be discretely added to a victim’s culinary sauce.
Harvard University Corroboration
Researchers at Harvard took more than a thousand men with early stage prostate cancer, and followed them for a couple years to see if there was anything in their diet associated with a resurgence of the cancer, such as a spread to the bone.
Compared to men who hardly ate any eggs, men who ate even less than a single egg a day had “a significant 2-fold increased risk of prostate cancer progression.” (Source)
“A plausible mechanism that may explain [the]…association between eggs and prostate cancer progression is high dietary choline.” (Ibid).
So what the facts show so far is this: Choline consumption is associated not just with getting cancer, and spreading cancer, but also with a significantly increased risk of dying from it because of its deleterious effect on metastases. Those who ate the most eggs “had a 70% increased risk of lethal prostate cancer.”, tell us the Harvard experts. (Ibid).
Another recent study found that men who consumed two and a half or more eggs per week ”had an 81% increased risk of lethal prostate cancer.” Now, it could just be the cholesterol in eggs that’s increasing fatal cancer risk, but it could also be that choline.
Cancer Biology 101
For cancer cells to thrive, they need, like all cells, food and in particular certain types of foods, one of which is lots of choline. By following the choline uptake in the body, one can track the spread of cancer throughout your body. (Source)
But why may dietary choline increase the risk of lethal prostate cancer? What could be the mechanism ? So far, it looks like the evidence is pointing at the TMAO, the trimethylamine oxide. The Harvard researchers speculated that the TMAO from the “high dietary choline [intake] may increase inflammation, and this may promote progression of prostate cancer to lethal disease.” (Source)
Corroborating this piece of assumption, the New England Journal of Medicine, that same Cleveland Clinic research team that did the carnitine study repeated the study. But, this time, instead of feeding people a steak, they fed people some hard-boiled eggs. And, just as they suspected, a similar spike in that toxic TMAO. So, it’s not just the red meat. And the link between TMAO levels in the blood and strokes, heart attacks, and death was seen even in low-risk groups like those with low-risk cholesterol levels. Thus, the up to now conclusion is established: eating eggs increases human early death risks regardless what the cholesterol level is, because of the choline.
Discussion & Conclusion
As the evidence shows, we are not designed to eat our animal mammal cousins. A dog can eat a ton of meat and all of that extra cholesterol, carnitine and choline and it will just go down as poop. Likewise with a fox, the fox can sneak in a chicken coop and make himself a huge omelette and all of that choline will not produce arterial clogging. For humans, animal choline, carnitine, cholesterol, heme iron, saturated fats, inter alia, all feed the bad gut bugs and cancer cells, they also damage healthy cells, including the endothelial structure of the vasculature, that which leads to plaque formation and atherosclerosis.
On the other hand, when humans eat a mostly plant-based diet, they develop friendly gut bacteria that will not only not produce TMAO and other deleterious substrates, but they will produce propionate and other key short-chain fatty acids, key neurotransmitters, hormones and among others, vitamins, all of which promote the symphony of Life and longevity.
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Pr Joubert (HMI director)
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