Do happy people live longer ?

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Sometime in late 2015, researchers seemed to deliver a blow to Pollyannas everywhere. The news? Happy people did not live longer than sad people, after adjusting for factors like the state of a person’s health. The study, published in prestigious medical journal The Lancet, looked at survey results from nearly 720,000 women and concluded that happiness, when considered independently, had no bearing whatsoever on how long people lived.

But many experts challenged that finding, taking issue with the study design, which removed as variables (or, in scientific terms, controlled for) things like how much a woman slept and whether she exercised. “The very reasons happy people live longer are some of the things the Lancet paper controlled for,” says Sarah Pressman, associate professor of psychology and social behavior at the University of California at Irvine, who has been researching happiness for about a decade. “Positive emotion is good for you.”

That may seem obvious, even to skeptics. Proving it scientifically can be tricky, however. Happiness studies usually rely on self-reported data, which is by nature subjective. Beyond that, it’s just difficult to navigate the channels of cause and effect, given the many factors that influence mood and health. Still, a large body of literature shows that there does appear to be a link between a good mood and a longer life.

A 2011 study published in Proceedings of the National Academy of Sciences found that older people who reported being the least happy died at nearly twice the rate in the next five years as people who reported being the most happy. Even after adjusting for factors like illness, finances and depression, people who were the happiest still had a 35% lower risk of death.

Another study of older adults found that happier people retained their physical function better than those who weren’t happy; their walking speeds even declined more slowly. And in one 2003 experiment, researchers found that when they exposed people to a common cold virus, happiness level was a strong predictor of who got sick and who stayed well, which they could see by measuring people’s mucus production and the levels of antibodies in their blood.

To Pressman, the existing research taken together settles the question: It does help to be happy. “The more interesting question is, Why?” she says. That’s a puzzle researchers are now trying to solve. Pressman and other researchers think happiness has specific benefits for the body that cannot be chalked up solely to healthy lifestyle choices, like exercising, or the absence of negative emotional factors, like chronic stress. Scientists already know that negative emotions can cause a cascade of biological reactions that harm the body. Chronic stress increases inflammation, and inflammation has been linked to a host of health problems. So it’s not a stretch to think that happiness, too, may lead to changes in the body’s systems that influence certain diseases. But what, exactly, does happiness do? How does a positive disposition affect somebody’s health? And, vitally, what are the best ways to get happier in a way that makes a difference?

Pressman isn’t sure yet, but she’s investigating one idea. Her experiments have found that people who smiled while receiving a needle injection rated the ordeal as 40% less painful than those who didn’t–a testament to faking it until you make it. And their heart rates didn’t increase as much in response to the stress of the injection, either.

“Now when I go to the doctor’s office, I smile when I get a shot,” she says. “It’s amazing that it works. We’re still trying to unpack why.”

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It makes so much intuitive sense that most people don’t question it—if you’re happy, or find ways to make yourself happier, you’ll be better off, both physically and mentally. No surprise either that some studies have also connected happiness to longer life.

But Bette Liu from the University of New South Wales and her colleagues are about to turn this truism on its head. In a study published in the Lancet, the researchers report that happiness doesn’t have much to do with living longer after all.

MORE: Why Chasing Happiness Might Be Making You Miserable

In the study, nearly 720,000 middle-aged women were followed long term to determine which factors were related to their mortality. They rated their happiness as well as answered questions about their health and other lifestyle habits, including whether they smoked, how much education they attained, their relationship status and the amount of stress they felt.

When Liu and her colleagues first correlated the women’s happiness scores with their mortality rates, they found that women who reported being happier tended to live longer, and the women reporting more unhappiness tended to die earlier. But when they controlled for factors such as health, they found that there was not statistically significant difference between the women who were happy and those who were unhappy. In other words, it wasn’t their happiness that was linked to mortality, but other things, most notably their health, that was really driving the connection.

MORE: How to Find Happiness: 3 Secrets From Science

“Our results show that being happier doesn’t make you live longer,” says Liu. “Being happier in itself doesn’t make you live longer. It’s the poor health of those individuals who are unhappy that actually explains why they might have higher death rates.”

Liu and her team came this conclusion by pooling together the results from asking the women questions about their happiness and their health and stress separately. “We asked very separate and discrete questions about happiness, health, stress, how relaxed people felt and how often they felt in control,” says Liu. They also looked among just women who reported being in good health and did not find differences in mortality among those who said they were happy v those who were unhappy. The also did not find any differences when they looked just at women who reported being in poor health.

MORE: The Most Proven Technique For Increasing Long Term Happiness

“So after we account for poor health in people who report being unhappy, there are no differences in death rates among unhappy and happy people,” she says.

But how convinced is she that she’s truly isolating the effect of happiness? “It’s a difficult question,” says Philipe de Souto Barreto, from University Hospital Toulouse who wrote an editorial accompanying the study. “Each person has a different concept of happiness — these authors defined happiness with a single question of rating happiness.” But, he notes, it’s a first attempt to address the question of whether happiness is actually a stand-in for a variety of other factors that could be truly driving mortality risk. Happiness (or unhappiness) could be a confounder for things such as health and stress.

Yet it’s not clear whether it will be possible to parse out the effect of just happiness, since people intuitively incorporate other things into their definition of happiness. “This is still research that is at the beginning of its development,” says Barreto. “We have a lot to learn yet.”

Christian is presently working on a new book on Holistic Medicine and Biogerontology, whose content invokes the compelling evidence that supports the following assertion: humans have been genetically designed to live a happy and healthy lifespan to at least 120 years. On this age limit, both evolution-based Science (Cf the Hayflick's limit) and the Bible (Genesis 6:3) concur. The “Joie de Vivre” Vibe that can eradicate today’s chronic disease epidemics and un-necessary suffering is thus within reach. See link on mission for more details.

Posted in Longevity Medicine, Anti-Aging, Gerontology, Telmomeres, Telomerase, Caloric Restriction, mTOR, Sirtuins, Protein Misfoldment

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